2018 ASBMB FELLOWSHIP: JESS BRIDGFORD
Department of Biochemistry and Molecular Biology
University of Melbourney
Jess Bridgford completed a Bachelor of Biomedical Science at Monash University in 2012. During her undergraduate studies, she undertook a Summer Vacation Project and a 3rd year Research Project in Biochemistry and Molecular Biology, under the supervision of Associate Professor Martin Stone. She then completed an Honours year in Biochemistry and Molecular Biology at the Monash Institute of Pharmaceutical Sciences, under the supervision of Associate Professor Stone and Dr Meritxell Canals. She graduated with First Class Honours and received the Bachelor of Biomedical Science Honours Prize for the highest achieving student. Her undergraduate and Honours research focused on the interactions of chemokines with their G protein-coupled receptors and the intracellular signalling pathways activated by these interactions. This work contributed to publications in Structure and Science Signalling.
In 2014, Jess received an Australian Postgraduate Award and a Bill Sawyer PhD Scholarship to undertake a PhD in the Department of Biochemistry and Molecular Biology at the University of Melbourne, under the supervision of Professor Leann Tilley. Jess is now in the final stages of writing her thesis. Jess’ doctoral research has focused on elucidating the molecular mechanism of action the first-line antimalarial, artemisinin, in the malaria parasite Plasmodium falciparum. Her research has revealed that artemisinin causes extensive protein damage and inhibits protein synthesis and degradation, leading to a build-up of toxic proteins that causes parasite death. Jess’ PhD work has contributed to publications in Nature Communications and PLOS Biology. Jess has also presented her research findings at numerous conferences and has been awarded oral and poster presentation prizes, including a poster prize at ComBio2017.
This ASBMB Fellowship will allow Jess to travel to Colorado, USA, where she will present her research findings to the Federation of American Societies for Experimental Biology (FASEB) Scientific Research Conference on Ubiquitin and Cellular Regulation.